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Search Results to Peter Crooks

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One or more keywords matched the following items that are connected to Crooks, Peter

Item TypeName
Concept Drug Evaluation, Preclinical
Concept Drug Screening Assays, Antitumor
Academic Article Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents.
Academic Article Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4.
Academic Article An in vivo evaluation of the antiseizure activity and acute neurotoxicity of agmatine.
Academic Article Antileukemic activity of aminoparthenolide analogs.
Academic Article Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity.
Academic Article Indolyl-quinuclidinols inhibit ENOX activity and endothelial cell morphogenesis while enhancing radiation-mediated control of tumor vasculature.
Academic Article Microwave assisted synthesis and in vitro cytotoxicities of substituted (Z)-2-amino-5-(1-benzyl-1H-indol-3-yl)methylene-1-methyl-1H-imidazol-4(5H)-ones against human tumor cell lines.
Academic Article Synthesis and in vitro evaluation of N-alkyl-3-hydroxy-3-(2-imino-3-methyl-5-oxoimidazolidin-4-yl)indolin-2-one analogs as potential anticancer agents.
Academic Article One-pot multicomponent synthesis of indole incorporated thiazolylcoumarins and their antibacterial, anticancer and DNA cleavage studies.
Academic Article Aplysinopsin analogs: Synthesis and anti-proliferative activity of substituted (Z)-5-(N-benzylindol-3-ylmethylene)imidazolidine-2,4-diones.
Academic Article Inhibition of NF-?B and DNA double-strand break repair by DMAPT sensitizes non-small-cell lung cancers to X-rays.
Academic Article Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2.
Academic Article Aminoparthenolides as novel anti-leukemic agents: Discovery of the NF-kappaB inhibitor, DMAPT (LC-1).
Academic Article Synthesis and in vitro screening of novel N-benzyl aplysinopsin analogs as potential anticancer agents.
Academic Article The NF-kappaB inhibitor LC-1 has single agent activity in multiple myeloma cells and synergizes with bortezomib.
Academic Article Dimers of Melampomagnolide B Exhibit Potent Anticancer Activity against Hematological and Solid Tumor Cells.
Academic Article Discovery of non-peptide, small molecule antagonists of a9a10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.
Academic Article Anti-cancer activity of carbamate derivatives of melampomagnolide B.
Academic Article 5-((1-Aroyl-1H-indol-3-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-diones as potential anticancer agents with anti-inflammatory properties.
Academic Article Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents.
Academic Article Synthesis and anti-proliferative activity of aromatic substituted 5-((1-benzyl-1H-indol-3-yl)methylene)-1,3-dimethylpyrimidine-2,4,6(1H,3H,5H)-trione analogs against human tumor cell lines.
Academic Article 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1).
Academic Article Dioxol and dihydrodioxin analogs of 2- and 3-phenylacetonitriles as potent anti-cancer agents with nanomolar activity against a variety of human cancer cells.
Academic Article Lobelane analogues containing 4-hydroxy and 4-(2-fluoroethoxy) aromatic substituents: Potent and selective inhibitors of [(3)H]dopamine uptake at the vesicular monoamine transporter-2.
Academic Article Identification of resveratrol analogs as potent anti-dengue agents using a cell-based assay.
Academic Article Identification of a melampomagnolide B analog as a potential lead molecule for treatment of acute myelogenous leukemia.
Academic Article Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells.
Academic Article Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats.
Academic Article Succinamide derivatives of melampomagnolide B and their anti-cancer activities.
Academic Article Development of a GC-MS assay for the determination of fentanyl pharmacokinetics in rabbit plasma after sublingual spray delivery.
Academic Article Synthesis and Evaluation of 2-Naphthaleno trans-Stilbenes and Cyanostilbenes as Anticancer Agents.
Academic Article A novel tetrazole analogue of resveratrol is a potent anticancer agent.
Academic Article Polyamine modulation of NMDARs as a mechanism to reduce effects of alcohol dependence.
Academic Article Antitumor properties of novel sesquiterpene lactone analogs as NF?B inhibitors that bind to the IKK? ubiquitin-like domain (ULD).
Academic Article Biobanked Glioblastoma Patient-Derived Organoids as a Precision Medicine Model to Study Inhibition of Invasion.

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  • Drug Evaluation Preclinical